So I’ve did a genetic testing for the usual curiosity about heritage (at myheritage.com). And looked around what else can be done with one’s DNA sequence And found a site: https://dna.land/ where it shows a genetic nearsightedness trait. It’s a free site, made by some researcher from the Columbia University and New York Genome Center (check the help page for more info). You cannot get your DNA sequence from this site, but you can upload there your data if your have it from some other.
Their analysis uses this study for reference:
For me (again: had -4.25 myopia with heavy close-up use before founding endmyopia), my result is:
For me wife it said -1.4. She currently has 20/20 vision with lot of mobile phone and close-up, but she had -1.0 glasses with some astigmatism before, when she spent almost all of her day in close-up and slept only a few hours per day. She improved on her own when her lifestyle changed (less gaming, more driving).
For those not familiar with genetics, this result does not says that my eyes are -2.4 and will never be better. This only says that I’m predisposed to have this amount of nearsightedness, but the actual amount is determined by a lot of factor. For example there is a height trait too, and while I’m 178 cm high, my trait only says 170 cm. The difference most likely comes from strong steroid medication for asthma when I was a child (took them since 7). From their site:
This is the variance explained by the SNPs included in our analysis, and can be interpreted as the fraction of your prediction that is determined by the genetic variants that have been discovered. Because almost all human traits are determined by a combination of our genomes and environment, the prediction only takes into account the genomic component, and your trait may further be determined by your environment. Additionally, in almost all complex traits a large fraction of genetic variants thought to contribute an effect have yet to be identified, so these predictions represent only our best guess based on current genomic knowledge.
Based on this N=2 experience, it could be deduced that if you are more predisposed to myopia, the more easier you get pseudomyopia (I got it as soon as I went to school at 6,while for my wife it needed a lot more close-up), but it would be interesting to see other’s numbers Anyone else here had their DNA tested?