@Viceroy.Sam I’ll let experts jump in in case I’m all wet, but YES … enlarging fonts enables you to move your head farther from the screen - and that is clearly a good thing if you’re able to better (active) focus and relax that ciliary muscle. I do this regularly now and have found superb results in expanding my in-focus near field distance.
FYI, I also installed color “reverser” add-ins to my browser to convert the black text on white background to white text on black background. I’ve found that, in addition to enlargement, this also reduces glare and eyeball washout. YMMV but give it a try.